Dear All, 

You are invited to the December ReNaFoBiS/FRISBI Zoom webinar. 

When: Dec 8, 2021 04:00 PM Paris 

Webinar Speaker Dr. Wladek Minor (Harrison Distinguished Professor, Department 
of Molecular Physiology and Biological Physics, University of Virginia, USA) 

Topic: Structural Biology Response to Biomedical Threats 





Abstract: 

Structural information, mainly derived by X-ray crystallography and 
Cryo-Electron Microscopy, is the quintessential prerequisite for 
structural-guided drug discovery. However, accurate structural information is 
only one information necessary to understand the big picture of medical 
disorders. To provide a rapid response to emerging biomedical challenges and 
threats like COVID-19, we need to analyze medical data in the context of other 
in-vitro and in-vivo experimental results. This approach may revolutionize drug 
discovery, albeit only when these data are combined and analyzed with effective 
data management framework like Advanced Information System proposed in 2017. 
The recently published virusMED system is a blueprint for Advanced Information 
Systems. 
Short CV of Pr Wladek Minor 


Prof. Wladek Minor received his Ph.D. in 1978 from the University of Warsaw in 
Solid State Physics. After moving to the United States in 1985 and working at 
Purdue University, he gradually switched to macromolecular crystallography. He 
joined the University of Virginia faculty in 1995. He was tenured in 1998 and 
promoted to full professor in 2003. In 2016, he became Harrison Distinguished 
Professor of Molecular Physiology and Biological Physics. He has been 
developing experimental protocols and computational methods for neutron 
scattering and X-ray diffraction since graduate school. After starting his 
independent career, he continued developing software within HKL, HKL-2000, and 
HKL-3000. He also worked on advanced solutions to other crystallographic 
problems: (a) Identification and refinement of metals in macromolecular 
structures; (b) Determination and analysis of macromolecular structures related 
to drug transport and drug discovery; (c) Reproducibility, ligand 
identification, and validation in structural biology; (d) Data mining, 
management, and access to primary experimental data; (e) Protocols and tools 
for more reliable structure determination, including the application of AI; (f) 
Analysis of COVID-19 structures and actions necessary to prepare for a possible 
future pandemic. He published more than 230 papers that attracted more than 
47,000 citations. He is a co-author of more than 450 Protein Data Bank 
deposits. Dr. Minor has trained over 110 people that are very successful in 
academia, industry, and medicine. Dr. Minor's research is often reported in 
general media outlets ( [ https://minorlab.org/news | https://minorlab.org/news 
] ), which helps taxpayers understand why investments in basic science are the 
best investments for the country's future. 

Register in advance for this webinar: 
https://us06web.zoom.us/webinar/register/WN_KnjC1dDBRZG4r8F6hQ_-VQ 


After registering, you will receive a confirmation email containing information 
about joining the webinar. 
Best 
Pr Jean Cavarelli 
[ https://www.renafobis.fr/ | https://www.renafobis.fr/ ] 
https://www.renafobis.fr/ 


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