Dear All,I am working on structures where Methionine is important in binding of peptides to the MHC protein complex.Would anyone kindly like to share their knowledge about anything they find it important about this particular amino acid structurally? Sharing a paper or just few comments will be greatly appreciated. I know my question may sound very general (and kind of superficial) but there is definitely a reason, that I don't know and might be already known, why certain peptides (like CLIP) are rich in Methionine, and that lowers their affinity of binding.Thank you and sorry to disturb you all.Best regards,Samer
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