S-hydroxycysteine can cartainly show up under nonreducing storage or
crystallization conditions, as an artifact.

Cheers,

Roger Rowlett

On Fri, Mar 27, 2020, 5:45 PM Chris Fage <[email protected]> wrote:

> Hi Richard,
>
> I recently observed the sulfenic acid derivative of a cysteine residue
> (S-hydroxy-Cys, ligand ID CSO) in one of my high-resolution maps. Could it
> be possibly be this, H-bonded to a nearby water molecule?
>
> Best wishes,
> Chris
>
>
> On Fri, Mar 27, 2020 at 21:33 Paul Emsley <[email protected]>
> wrote:
>
>>
>> On 27/03/2020 21:06, Cowan, Richard H. (Dr.) wrote:
>>
>>
>>
>>   although [BME] seems unlikely, since the crystallized protein is a Fab.
>>
>>
>> I don't follow.
>>
>>
>>
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