Dear BB Users, Within my unit cell, I see overlapping spherical blobs of Fo-Fc and 2Fo-Fc density in Coot. These blobs appear directly at the symmetry boundary, such that building a water molecule at the position results in overlaid symmetry-related molecules (see water 420, between three copies of His253). Is there a way to add this water without suffering from symmetry clashes, or should the density be ignored? Thanks in advance for your suggestions.
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