Pavel,
Sorry for an unclear sentence. What I meant was:
My conclusion is that "no fill-in" option might be tried at some stages
for datasets with low high res completeness. But, if a dataset ALSO has
low completeness in low-medium shells, then extra caution should be
applied. In my case, 2fofc maps looked really weird, likely due to low
res completeness and "no fill-in".
Thanks for sharing great example!
Ivan
On 8/7/19 17:18, Pavel Afonine wrote:
Hi Ivan,
My conclusion is that "no fill-in" option might be tried at some
stages, but with caution, especially for datasets with poor low res
completeness.
I'm guessing you really meant *high*, not low. More or less repeating
what others said already.. Correcting for low res completeness doesn't
add high-res details and so has lesser risk of introducing model bias at
atomic level. Contrary, filling in high-res terms is likely to
noticeably bias the map at atomic level of detail.
Here is one of my favorite examples of what missing low-res data can do
to your map:
http://cci.lbl.gov/~afonine/tmp/1nh2.pdf
Pavel
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