The Zhang Lab (zhanglab.bio) focuses on discovering and harnessing novel biological systems for development as molecular tools. In addition to our work with CRISPR-Cas systems, we have recently identified a number of additional exciting biological systems and we are working to understand their function and mechanisms. We are looking to recruit a sharp, experienced, creative Structural Biologist to lead projects aimed at mechanistically characterizing these novel systems and rationally engineering them for use as biotechnologies. The candidate will pursue his/her own structural biology projects within the group, collaborating with existing lab members or new hires as needed to advance the projects. Candidate must have strong background in biochemistry and structural biology research with successful demonstration of the ability to solve protein structures, and of particular interest, protein assemblies including RNA and DNA molecules. The ideal candidate will also possess superior experimental planning and execution skills, an open mind, curiosity about molecular mechanisms, and a strong desire to tinker.
The Zhang lab is a member of the Broad Institute of MIT and Harvard and McGovern Institute at MIT, and a part of the greater Boston life-science community including MIT and Harvard with ready access to structural biology resources, beamlines and Krios Cryo-TEM. Our lab is a fun, vibrant, fast-paced, result-driven, and collaborative environment with state-of-the-art research facilities and support from NIH, HHMI, and various foundations and philanthropies. We are a unique multidisciplinary lab working to bridge fundamental biology and development of biotechnology. The Broad Institute of MIT and Harvard offers an outstanding place to work. The workplace culture is diverse, dynamic, progressive, and supports a healthy work-life balance. To support this mission, we strive for a workplace culture that supports diversity, intellectual curiosity, flexibility, and integrity. Broad employees receive a generous benefits package (including a highly competitive salary, dental, vision and health insurance, retirement plan, and additional benefits) and a range of possibilities for career advancement. Details on our benefits package can be found here - https://www.broadinstitute.org/benefits/benefits-working-broad PRINCIPAL DUTIES AND RESPONSIBILITIES: · Develop, lead, and execute research projects · Stay current on the field and think deeply about creative new ways to have an impact · Contribute to the lab through teamwork and discussion · Help to train, supervise, and mentor junior staff as needed MINIMUM QUALIFICATIONS: · PhD in relevant field (structural biology, biochemistry, biophysics, molecular biology) · Extensive experience with biochemical, structural, and/or biophysical experimental techniques · Demonstrated scientific contributions to the field · Proven ability to efficiently and effectively solve problems Contact: zhangoff...@broadinstitute.org<mailto:zhangoff...@broadinstitute.org> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
