Dear CCP4BB-Users,
On behalf of Prof. Thilo Stehle I would like to post a job offer for two
PhD positions at the Interfaculty Institute of Biochemistry.
Best Regards,
Georg
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*PhD positions in Structural Biology at the Interfaculty Institute of
Biochemistry
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We offer PhD positions in the group of Professor Stehle at the
Interfaculty Institute of Biochemistry, University of Tübingen. Our
group is interested in visualizing interactions between pathogens and
hosts in order to describe the mechanisms of pathogen engagement of
target cells and to provide a basis for vaccine and drug design. For
more information about our research, visit our home page
(https://uni-tuebingen.de/de/45823) or the homepage of the ViroCarb
research consortium coordinated by our group (https://www.virocarb.de
<https://www.virocarb.de/>).
The successful candidates will work on the structural and functional
characterization of virus-glycan interactions and on the
structural and functional analysis of enzymes involved in cell wall
synthesis and degradation in pathogenic bacteria (see selected
publications below for examples of our work). We seek highly motivated
individuals with a Master degree in a relevant field (e.g. biochemistry
or chemistry). The ideal candidates will have practical and theoretical
knowledge in construct design and optimization as well as protein
production and purification. Experience in structure determination
methods and other biophysical methods is an advantage. We expect
excellent communication skills, willingness to work in a
team, dedication and motivation and the ability to design, plan
and interpret experiments in an independent manner. The ability to
communicate in english is essential, and a good working knowledge of
german will be advantageous but is not mandatory.
The salary will be based on German federal TV-L 13 (65%). The positions
are fully funded and available immediately. Applications will
be considered until July 15, 2019. The University of Tübingen is an
equal-opportunity employer and is committed to employ more handicapped
individuals and especially encourages them to apply. Applications of
women are explicitly encouraged.
Applications including contact information (E-mail, phone, or Skype),
CV, research experience, copy of the Master degree certificate, and
contact information of two persons for references should be send as
single pdf document (max. size 3 MB) toapply2ste...@gmail.com
<mailto:apply2ste...@gmail.com>
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*References:*
Gerlach et al. (2018). Methicillin-resistant Staphylococcus aureus
alters cell wall glycosylation to evade immunity. Nature /563/, 705-709.
Lenman et al. (2018). Polysialic acid is a cellular receptor for human
adenovirus 52. Proc. Natl. Acad. Sci. U S A. /115/, E4264-E4273
Ströh et al. (2015). Trichodysplasia Spinulosa-associated Polyomavirus
Uses a Displaced Binding Site on VP1 to Engage Sialylated Glycolipids.
PLoS Pathog. /11/, e1005112.
Blaum et al. (2015). Structural basis for sialic acid-mediated
self-recognition by complement factor H. Nat. Chem. Biol. /11/, 77-82.
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