Dear all, I have two open to work on fragment/XChem-related methodology for structure-based compound design.

Team Leader (applications close next *Weds 1st May*):  full ad here <https://www.thesgc.org/careers/oxford/sgc-oxford-team-leader-xchem>, summary:

   /We are recruiting an experienced computational chemist or
   scientific programmer, to head the Fragalysis project for automating
   fragment hit progression, part of the XChem collaboration between
   SGC and Diamond...  The //Fragalysis
   <https://fragalysis.diamond.ac.uk/>//project leader will be tasked
   with converting the existing proof-of-concept tool into a
   production-level system that is routinely usable for analysing XChem
   results and designing and acquiring follow-up compounds. This will
   entail setting the scientific direction and priorities of the
   project through close and continuous interaction with expert and
   novice users; coordinating a growing team of scientific programmers
   and contractors; liaising with and expanding a wide and
   international set of collaborators and contributors; securing
   further funding for the project; helping supervise students; and
   developing specific methodologies of their own./


Postdoc (closing *Weds 15th May*):  full advert here <https://www.thesgc.org/careers/oxford/sgc-oxford-postdoctoral-research-scientist-structure-based-drug-design>, this is a summary:

   /This role will be tasked with the design and acquisition of
   follow-up compounds based on fragment screening hits from the Target
   Enabling Package (//www.thesgc.org/tep
   <http://www.thesgc.org/tep>//) and Ultra-DD (//www.ultra-dd.org
   <http://www.ultra-dd.org>//) programs. The successful candidate will
   coordinate experimental validation of the newly designed compounds
   with collaborating scientists in order to progress them towards
   potent molecules.
   /

Cheers
Frank


--
Prof Frank von Delft
Associate Professor Principal Investigator: Protein Crystallography
Structural Genomics Consortium
Oxford University
+44 1865 617583 (office: W,F)

Principal Beamline Scientist: I04-1
Diamond Light Source
+44 1235 778997 (office: M,T,T)
+44 7471 026103 (mobile)

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