Dear all,
is there some kind of general trend if not consensus as how to refine
cryo-EM structures? What do people do for maps in the 3-4Å range,
pure RSR against the untouched map and that's it? Reciprocal space
refinement against the backtransformed structure factors from the map
but without touching the map?
I've even heard that some people "dare" to calculate 2mFo-DFc-maps....
Thanks a lot for your feedback.
Best,
Xavier
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