Dear Jorge This may not be exactly what you require, but there is a nice example of analysis in the shift of a coiled coil register herein:
Elife. 2018 Jun 5;7. pii: e34815. doi: 10.7554/eLife.34815. Asymmetric activation mechanism of a homodimeric red light-regulated photoreceptor. Best, Andy -----Original Message----- From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of jiu...@gmail.com Sent: 28 August 2018 14:04 To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] coiled-coil "degree" Dear all, I am working currently on a structure that, nicely, presents two different orientations between its domains when one compares monomers of the tetramer in the asymmetric unit. I notice, in this nature gift, that a helix, probably central (in its role) for the relation (orientation) between the two domains, assumes different relation to other one (helix, that belongs to one of the domains) such that they are (significantly) more or less "coiled-coiled"one to another, once the domains are in the "close" or "open" conformation. We have already analyzed the hydrogen bonds and salt bridges that are disrupted (or formed) due to the different (domain and helix) conformations. I wonder whether there is a metric (easy to evaluate) to characterize how much the two helix are "around each other" (id est, how much "coiled-coiled" they are) and, preferably, a software to calculate this metric. Thank you, Jorge State University of Ponta Grossa ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
