A postdoctoral fellow position is immediately available in the laboratory of Emmanuel Skordalakes at The Wistar Institute. The laboratory studies protein, nucleic acid assemblies that participate in the replication and maintenance of telomeres and have been implicated in a host of diseases including cancer. Areas of interest include the telomere replication and maintenance nucleoprotein complexes telomerase, CST and shelterin. We use a multidisciplinary approach involving biochemical, biophysical and cell based assays to address mechanistic questions related to the function of the above protein-nucleic acid assemblies. Our goal is to understand how telomeres are replicated, how shelterin and CST regulate this process and how dysfunction of these complexes leads to human disease. Information obtained from these studies will be used to identify activity modulators of telomerase and associated complexes as potential therapeutics for cancer and age-related diseases. The laboratory is located in the University City area of Philadelphia, in the heart of the University of Pennsylvania Campus. Both the Wistar Institute and the University of Pennsylvania provide resources to conduct cutting edge collaborative research, outstanding intellectual environments and state-of-the-art facilities. We are looking for highly motivated candidates that have recently acquired or will be acquiring a Ph.D. in biochemistry, structural biology or a related field and have a record of peer reviewed publications. Additional information regarding our research program can be found at the laboratory's web sites http://webdev.chem.upenn.edu/chem/research/faculty.php?id=52 http://www.wistar.org/lab/emmanuel-skordalakes-phd Interested applicants should e-mail their CV along with a cover letter briefly describing their research accomplishments and current research interests to Emmanuel Skordalakes, Ph.D., Associate Professor (sko...@wistar.org<mailto:sko...@wistar.org>). Emmanuel Skordalakes, Ph.D. Associate Professor Gene Expression and Regulation Program
The Wistar Institute 3601 Spruce St<x-apple-data-detectors://0/0> Philadelphia, PA 19104<x-apple-data-detectors://0/0> 215-495-6884<tel:215-495-6884> Office 215-898-2202<tel:215-898-2202> Lab sko...@wistar.org<mailto:sko...@wistar.org> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
