The “Structural Glycovirology” group at Freie Universität Berlin in Berlin-Dahlem is looking for an enthusiatic postdoctoral scientist with a strong background in structural biology, holding a PhD in Biochemistry, Biology or related subjects.
Carbohydrates densely cover every living cell and thus it is not a surprise that many human viruses interact with carbohydrates as receptors on their host cells in order to initiate infection. At the same time, viruses also encounter carbohydrates on their way from one host cell to another. The specificity and affinity of viral proteins for carbohydrates determines viral spread, transmission and pathogenesis. We use glycobiology and biophysics approaches to determine the specificity of viral proteins for carbohydrates and solve the structures of cognate protein-carbohydrate complexes by x-ray crystallography. Structural information is the key to understanding these protein-carbohydrate recognition processes, which are less well understood than protein-protein or protein-nucleic acid interactions. We are looking for - A strong background in the structure determination of proteins and/or protein-ligand complexes by x-ray crystallography, NMR or cryo-EM - Expertise in recombinant protein expression and protein purification – familiarity with different protein expression systems is helpful - The candidate should be interested in biochemical and biophysical approaches to define protein-ligand interactions such as ELISA, FACS, ITC, SPR, or NMR. - The candidate should be willing to learn about glycobiology and virology. - The candidate is expected to be a team player who fits into a multinational and multidisciplinary research environment. - Confidence in spoken and written English is a requirement. We offer The “Structural Glycovirology” group is a newly established research group funded by the Emmy Noether Programme of the Deutsche Forschungsgemeinschaft (DFG). The group is embedded in the Laboratory of Structural Biochemistry of the Freie Universität Berlin with state of the art facilities for protein expression and production. The Institute of Chemistry and Biochemistry is well equipped for x-ray crystallography and NMR, and is expanding its CryoEM equipment. We also have direct access to beamlines at BESSY II synchrotron through the Joint Berlin MX Laboratory. A friendly and multidisciplinary environment provides stimulating grounds for collaboration with groups in biophysics, cell biology and chemistry. We offer a full-time position available now until 30 April 2020. Contact Please submit your electronic application to me (ursula....@fu-berlin.de) including a concise description of skills, previous work experiences and scientific interest until June 25th, 2018. Also provide contact details for at least two scientific peers who can provide letters of recommendation. Looking forward to your response. With kinds regards, Ursula Neu Ursula Neu Emmy Noether Group Leader Laboratory of Structural Biochemistry Freie Universität Berlin Takustr. 6 14195 Berlin Germany phone: +49 30 838 57360 email: ursula....@fu-berlin.de http://www.bcp.fu-berlin.de/en/chemie/biochemie/research-groups/wahl-group/mitarbeiter/Dr_-Ursula-Neu.html ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
