Dear colleagues,
in the framework of a newly established DFG funded graduate program at
the Ruhr-University Bochum we are offering 12 PhD positions in the area
of microbial substrate conversion.
In my group, one candidate will focus on the stuctural aspects of
hydrogenases, using anaerobic crystallization and a variety of
biochemical and biophysical techniques in a close cooperation with two
other candidates in the Happe and Gerwert/Kötting labs.
Pls. have a look at the MiCon website for details about the project and
the application procedure:
http://www.rub.de/mikrobiologie/micon
Deadline for applications is already 22nd of May, 2018!
All the best,
Eckhard
Selected references:
Esselborn J, Muraki N, Klein K, Engelbrecht V, Metzler-Nolte N, Apfel
U-P, Hofmann E, Kurisu G, Happe T. 2016. A structural view of synthetic
cofactor integration into [FeFe]-hydrogenases. Chem. Sci. 7:959–968.
Noth J, Esselborn J, Güldenhaupt J, Brünje A, Sawyer A, Apfel U-P,
Gerwert K, Hofmann E, Winkler M, Happe T. 2016. [FeFe]-Hydrogenase with
Chalcogenide Substitutions at the H-Cluster Maintains Full H2 Evolution
Activity. Angew. Chem. 128:8536–8540.
Winkler M, Senger M, Duan J, Esselborn J, Wittkamp F, Hofmann E, Apfel
U-P, Stripp ST, Happe T. 2017. Accumulating the hydride state in the
catalytic cycle of [FeFe]-hydrogenases. Nature Communications 8:16115.
--
Prof. Dr. Eckhard Hofmann <eckhard.hofm...@bph.ruhr-uni-bochum.de>
Ruhr-Uni Bochum
AG Proteinkristallographie, LS Biophysik, ND04/318
44780 Bochum
Tel: +49-(0)234/32-24463, Sekr. -24461, FAX: -14762
ORCID: 0000-0003-4874-372X
