Dear all, How observation is to parameter ratio is determined for a crystal structure. Suppose If we have only one observation for each parameter at a resolution of say 2.9 Angstrom, how terribly it is easy to overfitt for the data to get a misleading agreement between model and experiment ? Is there any thumbrule for this ratio, and how it is dependent on the resolution of the data. Please shed some light on these aspects. Thank you With kind regards Prem
-- With kind regards, Prem Prakash PhD Research Scholar Protein Crystallography Lab Biosciences and Bioengineering IIT Bombay
