Shankar, It looks like Acetyl coA to me.
Best wishes, - Allister > On 10 Jan 2018, at 04:09, Shankar Prasad Kanaujia <spkanau...@gmail.com> > wrote: > > Dear All, > > Wishing you all a very happy and prosperous new year 2018.... > > We have recently solved a structure which contains a huge density in the > active site. We modelled a molecule fitting the electron density (please see > the attached figures). However, we could not find any known molecule similar > to the fitted molecule either in PDB or PubChem databases. Thus, we are not > able to correlate its existence in cell. > > The protein was expressed in E. coli cells. The structure is solved at 1.85 > Angst. We have not added any molecule like this in any step of the > experiments. > > Looking forward to having some ways to figure out this problem. > > With best regards, > Shankar > <ligand1_density.png> > > -- > Shankar Prasad Kanaujia, Ph.D. > Associate Professor > Department of Biosciences and Bioengineering > Indian Institute of Technology Guwahati > Guwahati - 781039 Assam, India > Tele: 0361 258 2228 > Fax: 0361 258 2249 > Email: spkanau...@iitg.ernet.in <mailto:spkanau...@iitg.ernet.in> > Homepage: http://www.iitg.ernet.in/spkanaujia/ > <http://www.iitg.ernet.in/spkanaujia/> > Google Scholar: https://scholar.google.com/citations?user=Zt4JSNYAAAAJ&hl=en > <https://scholar.google.com/citations?user=Zt4JSNYAAAAJ&hl=en> > <ligand1.png> ----------------- Allister Crow School of Life Sciences University of Warwick
