This is an extraordinary opportunity join the efforts to develop a new class of protein therapeutics to cure Type 1 Diabetes in laboratories of Professors John Williams, Enrique Casimiro, and Bart Roep at the Beckman Research Institute and the Diabetes & Metabolism Research Institute at the City of Hope, a world class institute that played essential roles in the development and translation of recombinant insulin and humanization of monoclonal antibodies and continues to lead in the development CAR T cell and other novel therapeutic approaches. The project will involve the rational design, production and characterization of novel biologics using technologies pioneered in the Williams lab and discoveries made in the Roep/Casimiro Labs. It is anticipated that the successful applicants will have the opportunity to participate in and translate their leads through pre-clinical development (see https://www.cityofhope.org/news/city-of-hope-sets-new-goal-for-type-1-diabetes-cure).
Responsibilities: Protein engineering, production, purification Biophysical characterization (SPR, ITC, AUC, CD) Assay development, interpretation, and troubleshooting Minimum Education and Skills Required for Consideration: PhD in biochemistry, molecular biology, protein chemistry, biochemical engineering or related field. Experience with protein expression and purification Excellent written and verbal communication skills Good problem solving skills Ability to conduct independent research Ability to supervise others and work effectively in a team Industrial experience a plus Apply at: https://chm.tbe.taleo.net/chm04/ats/careers/v2/viewRequisition?org=CITYOFHOPE&cws=49&rid=10137 --------------------------------------------------------------------- -SECURITY/CONFIDENTIALITY WARNING- This message (and any attachments) are intended solely for the individual or entity to which they are addressed. This communication may contain information that is privileged, confidential, or exempt from disclosure under applicable law (e.g., personal health information, research data, financial information). Because this e-mail has been sent without encryption, individuals other than the intended recipient may be able to view the information, forward it to others or tamper with the information without the knowledge or consent of the sender. If you are not the intended recipient, or the employee or person responsible for delivering the message to the intended recipient, any dissemination, distribution or copying of the communication is strictly prohibited. If you received the communication in error, please notify the sender immediately by replying to this message and deleting the message and any accompanying files from your system. If, due to the security risks, you do not wish to receive further communications via e-mail, please reply to this message and inform the sender that you do not wish to receive further e-mail from the sender. (LCP301) ---------------------------------------------------------------------