This is an extraordinary opportunity join the efforts to develop a new class of 
protein therapeutics to cure Type 1 Diabetes in laboratories of Professors John 
Williams, Enrique Casimiro, and Bart Roep at the Beckman Research Institute and 
the Diabetes & Metabolism Research Institute at the City of Hope, a world class 
institute that played essential roles in the development and translation of 
recombinant insulin and humanization of monoclonal antibodies and continues to 
lead in the development CAR T cell and other novel therapeutic approaches. The 
project will involve the rational design, production and characterization of 
novel biologics using technologies pioneered in the Williams lab and 
discoveries made in the Roep/Casimiro Labs. It is anticipated that the 
successful applicants will have the opportunity to participate in and translate 
their leads through pre-clinical development  (see 
https://www.cityofhope.org/news/city-of-hope-sets-new-goal-for-type-1-diabetes-cure).

 

Responsibilities:

    Protein engineering, production, purification
    Biophysical characterization (SPR, ITC, AUC, CD)
    Assay development, interpretation, and troubleshooting

 

Minimum Education and Skills Required for Consideration:

    PhD in biochemistry, molecular biology, protein chemistry, biochemical 
engineering or related field.
    Experience with protein expression and purification
    Excellent written and verbal communication skills
    Good problem solving skills
    Ability to conduct independent research
    Ability to supervise others and work effectively in a team
    Industrial experience a plus 

Apply at:

https://chm.tbe.taleo.net/chm04/ats/careers/v2/viewRequisition?org=CITYOFHOPE&cws=49&rid=10137

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