Dear Crystallographer-Bioinformaticians, Is anyone aware of a way to tweak BLAST or similar software to be able to specify certain residues to be absolutely required, e.g., active site residues? I guess one can winnow broad-scale resuts with scripts, but it would seem to be a pretty common type of thing to do, and might change results slightly a la psi-BLAST.
All the best, Jacob Keller +++++++++++++++++++++++++++++++++++++++++++++++++ Jacob Pearson Keller Research Scientist / Looger Lab HHMI Janelia Research Campus 19700 Helix Dr, Ashburn, VA 20147 (571)209-4000 x3159 +++++++++++++++++++++++++++++++++++++++++++++++++ The content of this email is confidential and intended for the recipient specified in message only. It is strictly forbidden to share any part of this message with any third party, without a written consent of the sender. If you received this message by mistake, please reply to this message and follow with its deletion, so that we can ensure such a mistake does not occur in the future.
