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Postdoctoral Position in Structure and Function of G protein-coupled Serotonin Receptors and Neurotransmitter Transporters. A postdoctoral position is available in the research group of Daniel Wacker, Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York. Employment will commence in early Spring of 2018. The long term goal of the Wacker lab is to understand the structure, function and pharmacology of G protein-coupled serotonin receptors and neurotransmitter transporters, and leverage these data using structure based drug design to develop novel therapeutics. Serotonin signaling in the brain controls a variety of physiology related to mental health, including cognition, learning, and memory, and is targeted by illicit and therapeutic psychoactive drugs such as LSD, antidepressants, and anti-psychotics. Towards a molecular understanding of serotonin signaling, we will employ a combination of state-of-the-art structural (X-ray crystallography, cryo-EM) and pharmacological techniques. More information can be found at http://wackerlab.com/. Applicants should hold a PhD in a relevant subject area, such as membrane protein biochemistry or structural biology. Experience in recombinant membrane protein expression and purification, structure determination, or functional analysis using biochemical and biophysical techniques is essential. The ability to work in a team as well as good verbal and written communication skills are expected. Experience in protein x-ray crystallography and/or cryo-EM is an advantage. Applications including research interests and career aims, as well as a CV with publication record and contact information for three references should be send to: Daniel Wacker, PhD Assistant Professor Department of Pharmacological Sciences Icahn School of Medicine at Mount Sinai One Gustave L. Levy Place New York, NY 10029 daniel.wac...@mssm.edu
