You don't say what you mean by "too high", but if you are in a space group with multiple possible indexing conventions (eg different choices for the direction of b in a polar spacegroup) you can get very high Rmerge values. In the scalepack section of the old HKL manual ( http://hkl-xray.com/hkl-manual) there is a Reindexing scenario that explains how to approach this problem; the HKL matrices can be used as macros in HKL2000.
Best wishes, kmj On Mon, Apr 10, 2017 at 7:46 PM, 高艺娜 <gaoy...@cau.edu.cn> wrote: > Dear all, > For my crystal, I have to merge 3-4 sets of diffraction data using HKL2000 > program to meet requirements for data completeness, but the problem is the > Rmerge value was too high to go on every time. > Did anyone have met the same problem and how to solve it? or some tips for > solve this problem？ > > All comments will be appreciated! > > Best Regards, > > -- Kevin Jude, PhD Research Specialist, Garcia Lab Departments of Molecular & Cellular Physiology and Structural Biology Stanford University School of Medicine Beckman B177, 279 Campus Drive, Stanford CA 94305 Phone: (650) 723-6431
