Dear Crystallographers,

It is my recollection from a while ago that cryocooling to Helium temperatures 
has modest if any effects on protein structure or diffraction data quality, and 
I've found a couple of papers just now to that effect. Does anyone know 
differently? Do the b-factors even change?

Further, is anyone aware of a beamline which has really low temperature 
capability, ideally in conjunction with spectroscopic analysis?

All the best,

Jacob Keller



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Jacob Pearson Keller, PhD
Research Scientist
HHMI Janelia Research Campus / Looger lab
Phone: (571)209-4000 x3159
Email: kell...@janelia.hhmi.org<mailto:kell...@janelia.hhmi.org>
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