A postdoctoral fellow position is available immediately at the Paul Scherrer Institute in the group of Dr. Xiaodan Li at the Laboratory of Biomolecular Research (https://www.psi.ch/lbr/li_-xiaodan). The group has track record on structure determination of membrane protein using 2D and 3D crystals and is currently expanding the structure determination using to single particle cryo-EM. We are looking for a single particle cryo-EM postdoctoral research with experience in sample preparation and optimization, data analysis, processing and reconstruction. Previous experience working with membrane proteins will be an advantage but not a prerequisite.
The Laboratory of Biomolecular Research at PSI has all facilities and instruments for protein expression, purification, biochemical and biophysical analysis (https://www.psi.ch/lbr/laboratory-of-biomolecular-research), as well as the full access to the PSI crystallization facility and the Swiss Light Source synchrotron radiation facility (https://www.psi.ch/sls/pxiii/crystallisation-facility). The group benefits from the in-house 200 kV screening transmission electron microscope (JEOL JEM2200). Furthermore, the group has access to the center for cellular imaging and nano analytics (C-CINA) in the University of Basel including the K2 and Falcon II direct detector-equipped Titan Krios microscope for high-resolution imaging and Polara (300kV) with K2 and MediPix Direct electron detector for electron nanocrystallography (https://c-cina.unibas.ch/). Interested candidates could send an e-mail to xiao...@psi.ch for informal inquires. The application should include a cover letter describing the candidate`s research interests and motivation to apply, the CV and list of publications, and contact details of three referees.
