Dear ccp4bb, I have a post-doc position available in my lab (see below) and would be grateful if this advert could be passed on to suitable candidates.
Thanks, Mike SENIOR RESEARCH OFFICER (PDRA) - 18 months. Ref RE815 Location School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ. Salary £31,342 per annum Closing date 30 June 2015 Post to start as soon as possible following interviews. The School of Biological Sciences at the University of Essex is seeking to recruit a motivated and enthusiastic Senior Research Officer to work in the Structural Biology group under the supervision of Dr Michael Hough (Principal Investigator) on an 18 month project funded by the Biotechnology and Biological Sciences Research Council (BBSRC). This project integrates rapid room temperature protein crystallography with large scale QM/MM simulations to elucidate a ‘minimum catalytic core’ model for the complex chemistry of key multi-copper and haem-cupredoxin containing nitrite reductase enzymes that are vital components of the global nitrogen cycle. Your role in this work as a structural biologist will be to develop and apply methodology to measure room-temperature diffraction data from protein crystals and to analyse sequences of many structures measured from the same crystals in rapid succession. You will produce a detailed structural understanding of catalytic processes allowing the dynamic processes of catalytic regulation and control to be understood. The work will include elucidating the proton coupled electron transfer trigger-mechanisms that involves binding of nitrite and conversion to nitric oxide, the determination of efficient electron transfer pathways and the pathway(s) of solvent mediated electron transfer at the cytochrome(haem)-cupredoxin interface, and the critical ligand migration and escape pathways. The successful candidate will hold, or be in the final stages of completion of, a PhD in a relevant area, have experience in structural biology and will work in close collaboration with a senior research officer in computational biological chemistry and scientists at Diamond Light Source and the Science and Technology Facilities Council (STFC) Hartree Centre. Based at our Colchester Campus, appointment to this 18 month full-time, fixed-term post is immediately available. Please use the link below for a full job description, person specification and further information relating to this post. Please read this information carefully before applying for this post as it contains details of documents that must be attached to your application. Applications should be made on-line, but if you would like advice or help in making an application, or need information in a different format, please telephone (01206 874588/873521). http://jobs.essex.ac.uk/fe/tpl_essex01.asp?s=4A515F4E5A565B1A&jobid=84840,1258234865&key=156435086&c=51655614561223&pagestamp=sevqpdcsinmurxbzje Informal enquiries may be made to Dr Mike Hough maho...@essex.ac.uk<mailto:maho...@essex.ac.uk> or Dr Richard Strange stra...@essex.ac.uk<mailto:stra...@essex.ac.uk>
