Dear all,
I want to have a closer look at a conformational change in a multidomain
protein. We see clear changes from different structures but there is
evidence that the conformational changes might be larger than observed.
My idea is to get the transformation matrix of each residue (or of each
atom) to go from conformation 1 to conformation 2. These matrices could
be scaled to see where the domains might move.
So its a kind of morphing but extrapolating from a certain structural
change instead of interpolating between the two structures.
Has anybody came across this before and found a quick solution? Any hint
is appreciated.
Best regards, Guenter
