I’ll add to this that you should also set the relevant path in launchd.conf as well to access other external programs (SHELXC/D/E) when opening ccp4i via the Finder/Spotlight.
setenv PATH /where/ever/shelx Cheers, Aaron ------------------------------------------ Dr. Aaron Finke Postdoctoral Fellow Swiss Light Source WSLA/217 CH-5232 Villigen-PSI phone: +41 56 310 5652 e-mail: aaron.fi...@psi.ch<mailto:aaron.fi...@psi.ch> On May 5, 2015, at 11:00, Finke Aaron (PSI) <aaron.fi...@psi.ch<mailto:aaron.fi...@psi.ch>> wrote: Dear Mark, Indeed there is a way. You have to set the environment variable so that all Mac apps can access it. This is most easily done via launchd. In the Terminal, type ‘sudo vi /etc/launchd.conf’ and add the following text (the file will likely be blank): setenv SHARP_home /where/ever/SHARP/ Save, and reboot. Now when you access ccp4i in a Finder window or Spotlight, autoSHARP should be accessible. More info can be found here: http://stackoverflow.com/questions/135688/setting-environment-variables-in-os-x/3756686#3756686 I hope this works for you. (It worked for me.) Cheers, Aaron ------------------------------------------ Dr. Aaron Finke Postdoctoral Fellow Swiss Light Source WSLA/217 CH-5232 Villigen-PSI phone: +41 56 310 5652 e-mail: aaron.fi...@psi.ch<mailto:aaron.fi...@psi.ch> On May 5, 2015, at 1:17, Mark J van Raaij <mjvanra...@cnb.csic.es<mailto:mjvanra...@cnb.csic.es>> wrote: Dear All, when starting CCP4i via the icon, AutoSharp remains greyed out, suggesting it is not installed. However, when I start CCP4i in an XQuartz window (i.e. “ccp4i &”), AutoSharp can be run. I guess this may be because in first way my “.profile” file is not read, any ideas how to fix this? Greetings, Mark J van Raaij mjvanra...@cnb.csic.es<mailto:mjvanra...@cnb.csic.es> http://www.cnb.csic.es/~mjvanraaij