On Fri, 17 Apr 2015 15:00:12 +0000, Keller, Jacob <kell...@janelia.hhmi.org> wrote:
>>Finally, there is simply no downside in collecting more degrees with >>proportionally lower dose on the Pilatus. Merging the data recovers the >>_same_ signal. It has only advantages - so many that I won't write them up >>here with 1 finger on my tablet. > ...Up to the point at which one can no longer index/refine the frames > reliably. I agree. In addition, one also needs some reflections significantly higher than the noise to build up the reference profiles. > And it would be interesting to try to figure out what that point is, or how > to push it to even fewer photons. I have processed test data sets (measured at the SLS) which have only a few non-zero pixels on each frame. Can be nicely integrated - but it was insulin. > JPK best, Kay
