Dear friends, I would like to draw your attention to an opening in our structural biology group at Amgen San Francisco. Please apply through the web portal
http://careers.amgen.com/en/jobs/descriptions/scientist-protein-biochemist-crystallographer-south-san-francisco-job-5231739 The job description is at the end of this email. Cheers, Xiaoshan Min Molecular Structure Amgen San Francisco 650-2442412 Scientist - Protein Biochemist / Crystallographer Auto Req #: 25895BR Career Categories: Research Location: US - CA - South San Francisco Amgen Job Description Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is expanding our Research and Development facilities in South San Francisco, CA (ASF). We are looking for a highly motivated and talented protein biochemist or crystallographer to join the ASF Structural Biology group. This laboratory provides comprehensive molecular insight and structure-based design for drug target assessment, mechanism of action, protein-protein and protein-ligand interactions, as well as protein engineering to facilitate drug discovery across various important therapeutic areas. The candidate will have the opportunity to contribute directly to the exciting drug discovery process through structural studies on a wide variety of important biological systems, including human integral membrane proteins. The candidate will be responsible for leading projects through the entire protein crystallographic process, including construct design, protein purification, characterization, crystallization, X-ray data collection, structure determination and analysis. The candidate will be working closely with molecular biologists and protein biochemists in the protein technology team. The candidate will also interact directly with computational and medicinal chemists and protein engineering teams for structure-based drug design projects. The candidate must have strong interpersonal skills to work in interdisciplinary project teams Basic Qualifications - Doctorate degree OR - Master's degree & 5 years of scientific experience OR - Bachelor's degree & 7 years of scientific experience Preferred Qualifications - PhD in protein biochemistry, crystallography, or related discipline with significant postdoctoral research experience - Proven ability to design and perform experiments from protein expression to structure determination - Knowledge of state-of-the-art membrane protein structural biology techniques including all aspects of construct design, expression, purification, crystallization screening/optimization (including LCP and LCP-FRAP) - Expertise in protein biochemical and biophysical characterization - Experience with X-ray free electron laser and/or cryo-EM will be highly desirable - Excellent presentation skills (written and oral) that enhance team-based progress are required - Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment Amgen is an Equal Opportunity/Affirmative Action employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, national origin, protected veteran status, or disability status.
