Hi Remie, You can add harmonic restraints for parts you do not want to move too much. Instructions could be found here: http://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/refmac/refmac_keywords.html#Harmonic
Regards Garib On 13 Aug 2014, at 15:44, Remie Fawaz-Touma <remiefa...@gmail.com> wrote: > Hi everyone, > > Does anyone know of a way to refine with CCP4 - Refmac5 (restrained > refinement is what I do) fixing a part of the the ligand? > > Thank you very much for your input, > > Remie Dr Garib N Murshudov MRC-LMB Francis Crick Avenue Cambridge CB2 0QH UK Web http://www.mrc-lmb.cam.ac.uk, http://www2.mrc-lmb.cam.ac.uk/groups/murshudov/
