To all who may be interested. Neil McDonald has asked me to forward this message to the bulletin board. Please reply to him at neil.mcdon...@cancer.org.uk and NOT to me.
Thanks Andrew ========================================================================= Postdoctoral Position (4 years), Structural Biology Laboratory London Research Institute (LRI), Cancer Research UK Structural Biology of Growth Factor Signalling A postdoctoral position is available in the Structural Biology Laboratory headed by Neil McDonald to work on molecular mechanisms underlying the assembly and activation of growth factor signalling complexes. The successful candidate will join a multidisciplinary group using structural biology, biochemistry, biophysics and cell biology. We are interested in how signals are initiated at the plasma membrane and are propagated into the cell nucleus. This project will focus on the RET receptor tyrosine kinase activation (see Plaza-Menacho et al. Mol. Cell 2014, Kjær et al. Nat. Struc. Mol. Biol. 2010 and Knowles et al. J. Biol. Chem. 2006). More information on our research activities is available at the lab website: http://www.london-research-institute.org.uk/research/neil-mcdonald. The postdoctoral fellow will join the lab at an exciting phase prior to the London Research Institute becoming part of the Francis Crick Institute (www.crick.ac.uk). The fellow will benefit from both the multidisciplinary environment in the lab and a highly collaborative LRI/Crick community. The lab has extensive crystallographic and robotics equipment with local access to electron microscopy, TIRF and confocal microscopes. We have regular access to synchrotron beamlines at Diamond and ESRF as part of a Cancer Block Allocation Group. The successful candidate will have a relevant PhD or be in the final stages of completing their PhD and have a strong interest in structural biology or cell signalling. Previous experience in protein purification, tissue culture, electron microscopy or crystallography would be an advantage. Informal enquires from interested individuals should be made by email to Professor Neil McDonald at neil.mcdon...@cancer.org.uk. Closing date for applications is sometime over the summer, 2014. -- Andrew Purkiss X-ray Laboratory London Research Institute Cancer Research UK
