Dear All
              I am planning to purify monoclonal antibody.  In this concern
I found Pseudospecific ligands such as histidine, tryptophan,phenylalanine
etc. can be used to purify a wide range of bio-molecules and especially
immunoglobulin. I wish to know the structural mode of binding of Histidine
(as affinity ligand) with Immunoglobulin.
Sanjit Kumar

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