Dear all,

Two PhD positions in structural biology are available in the newly established research group of Dr. Sebastian Geibel at the Institute for Molecular Infection Biology, University of Würzburg in Germany.

The PhD positions are funded by the Elite Network of Bavaria to investigate the type VII secretion system, which is used by pathogenic mycobacteria such as M. tuberculosis to subvert the human immune defence by the secretion of various proteins. The Geibel group aims to understand the molecular architecture of the type VII secretion system and to characterize the mechanism of protein secretion using a multidisciplinary approach employing a combination of structural biology, biophysical and biochemical techniques. The Geibel lab has access to state-of-the-art instruments and is integrated into a stimulating, collaborative research environment that includes the Institute for Molecular Infection Biology, the Rudolf Virchow Center for Experimental Medicine, the Biocenter, the University Hospital, and the Max Planck Research Groups for Systems Immunology in Würzburg.

PhD projects will involve structure-function studies on large membrane protein complexes using a variety of approaches including electron microscopy and/or X-ray along with complementary biophysical and biochemical methods. Applicants should have a strong background in molecular biology or biochemistry and a strong interest in either X-ray crystallography or electron microscopy. Previous experience in protein expression and purification as well as biophysical techniques to characterize protein interactions would be an advantage. Good English language skills are essential; knowledge of German is not required. The PhD positions are funded by the Elite Network of Bavaria for a period of 5 years. The salary will be according to the collective agreement (TV-L scale).

Please send applications and informal inquiries including a short letter of motivation detailing research interests and expertise, CV and contact information of two references as a single pdf file to [email protected]. In case of equivalent qualifications, disabled applicants will be preferentially considered.

Dr. Sebastian Geibel
Institute for Molecular Infection Biology
University of Würzburg
Josef-Schneider-Strasse 2, Haus D15
97080 Würzburg
Germany

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