Dear all,
You are invited to apply for a postdoctoral position in the structural biology
lab of McArdle Cancer Institute of University of Wisconsin at Madison. We are
interested in understanding the structural basis and mechanisms of
cancer-related cell signaling proteins and protein complexes. One important
focus of the study is to elucidate mechanisms of protein chaperones in
modulating the function of signaling proteins with important relevance to
cancer, such as protein phosphatase 2A (PP2A) complexes, viral kinases, nuclear
receptors, and RNA interaction proteins, using X-ray crystallography, NMR, FRET
imaging and diverse biochemical, biophysical, and cell biology approaches. Some
results related to this aspect can be found in our recent publications
(Molecular Cell 41, 1–12, 2011; Nat. Commun., 4:1699, 2013; Cell Research,
24(2):190-203, 2014).
The lab is equipped with a state-of-the-art setup for x-ray crystallographic
studies, including crystallization robot, and advanced imaging system for FRET
study in mammalian cells. The researcher will work in a multidisciplinary
setup, including cell biology, biophysics, proteomics, and protein
biochemistry, in addition to protein crystallography.
Candidates should hold a PhD in protein biochemistry and crystallography and
have a good working knowledge of molecular biology techniques. Experience in
NMR spectrometry is highly appealing. The candidates should be highly
motivated, goal-driven, and dedicated individuals who can think critically and
work both independently and collaboratively with good verbal and written
communication skills. It is also important that the candidates are creative in
problem solving and have a strong desire to seek answers to questions related
to the molecular basis of cellular processes. Experience in cell culture
techniques and writing scientific research papers would be advantageous.
Postdoctoral training grant is available for eligible candidates. Eligibility
to training grant is appealing, but not essential.
This is a full-time position with a starting salary of $41,000 – 45,000 per
year depending on skills and experience.
Review of applications will begin immediately and continue until the positions
are filled.
To apply: Please send a cover letter, CV and the names and contact information
for three references to Dr. Yongna Xing, 1400 University Avenue, McArdle
Laboratory for Cancer Research, University of Wisconsin-Madison-Madison, WI
53706. Email: yx...@oncology.wisc.edu.
Yongna Xing, Ph.D.
