What about this one?

http://dx.doi.org/10.1107/S0907444912002946

Although the excitation is x-rays and not visible light, you are still conceivably "identifying protein crystals with visible light". Seems to mostly come from aromatics. Not sure how much damage you have to do to get "enough" XEOL signal. Probably depends on how dark the room is.

-James Holton
MAD Scientist

On 2/15/2014 8:36 AM, Richard Gillilan wrote:
My original question was:

Some years ago, I remember hearing about a microscope that used *visible* light 
combined with some proprietary image processing algorithm to
distinguish between protein crystals, salt, and background. I can't remember 
the company name or researchers involved.

Has anyone here heard of this?
None of the answers I received sound like what I remember. Nonetheless, there 
are two companies that apparently offer visible-light technology for 
recognizing crystals:

(a) Tritek: proteincrystalimaging.com/index.php
(b) Jan Scientific: (VISEX) see smb.slac.stanford.edu/news/Visex.pdf  (their 
listed products seem to be UV-based, but apparently this one is visible.)

Both of these are proprietary commercial products, so it is impossible to know 
exactly what they are doing.

Richard Gillilan
MacCHESS

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