But you have not tested in the beam if the visually happy crystals diffract right ? I would do this first before consuming your precious ligands in worthless drops. Jürgen
On Sep 12, 2013, at 10:34 AM, Christopher Browning wrote: Right now I've tried 5, 10 and 16% DMSO (due to variations in the final ligand conc.) and the crystals visually look happy. ...................... Jürgen Bosch Johns Hopkins University Bloomberg School of Public Health Department of Biochemistry & Molecular Biology Johns Hopkins Malaria Research Institute 615 North Wolfe Street, W8708 Baltimore, MD 21205 Office: +1-410-614-4742 Lab: +1-410-614-4894 Fax: +1-410-955-2926 http://lupo.jhsph.edu