We are looking for one or two highly motivated and multi-talented postdoctoral researcher(s) to join a collaborative project studying the structure and mechanism of circadian clocks (See Huang et al. <http://www.sciencemag.org/content/337/6091/189.abstract> 2012 Science). The overall goal of the project is to understand how various multi-domain clock proteins interact with each other; and how these interactions modulate the clock-mediated transcription activation. Person(s) working on this project will have a unique opportunity to gain some unusual insights into the molecular clockworks governing our sleep-wake cycles.
Candidates should have a Ph.D. degree in a relevant field and must be proficient in molecular cloning, protein expression, purification, crystallization, and X-ray crystal structure determination. Additional experiences in eukaryotic protein expression systems, cell culture, various biochemical and biophysical techniques to study protein-protein interactions are also highly desirable. To apply, please email CV and contact info of two or more referees to zh...@chop.swmed.edu. All the Best, Hong Zhang, Ph.D. Associate Professor Department of Biophysics and Department of Biochemistry UT Southwestern Medical Center at Dallas 4323 Harry Hines Blvd. Dallas, Texas 75390-8816 Phone: 214-645-6372 Fax: 214-645-5948 http://profiles.utsouthwestern.edu/profile/23445/hong-zhang.html