On 03/19/13 14:41, Jacob Keller wrote:
I don't understand this argument, as it would apply equally to all features of the theoretical LUCA (protein and DNA sequences, etc). To make it logically sound, I think you have either to include some kind of super-high boundary to getting to other possible conventions (you probably imply this) or, as I have suggested, it may be a particularly good, if not the best, solution (a global minimum, one might say). The first hypothesis is similar to the QWERTY keyboard, which is cemented in place by many factors, whereas the second is more "survival of the fittest."
It would not be a safe idea to assume that LUCA was a single cell with a single chromosome (i.e. like a modern bacterium.) It would also not be safe to assume that viruses and horizontal gene transfer were not around at that time.
As I mentioned privately, I think the relevant slogan would be "winner take all" rather than "survival of the fittest."
Another possible explanation for having a recognition tag at the beginning of each transcribed gene: to distinguish between host and virus. This does not imply that Met has any specific advantage over any any other tag which might have been chosen.
-- ======================================================================= All Things Serve the Beam ======================================================================= David J. Schuller modern man in a post-modern world MacCHESS, Cornell University schul...@cornell.edu