yes - but keep in mind your protein is in the context of the crystal lattice, so flexible regions in solution are likely to be stabilized in the crystal lattice. So if you color by B also look at the symmetry mates. And you should also submit both structures to the TLSMD server and look at those results. http://skuld.bmsc.washington.edu/~tlsmd/
Jürgen On Mar 3, 2013, at 4:35 PM, Faisal Tarique wrote: > Dear all > > Can B factor in the crystal structure be the criteria to look into the > flexibility of a region or domain.? Also if two structures are at different > resolutions. > > Faisal > -- > ...................... Jürgen Bosch Johns Hopkins University Bloomberg School of Public Health Department of Biochemistry & Molecular Biology Johns Hopkins Malaria Research Institute 615 North Wolfe Street, W8708 Baltimore, MD 21205 Office: +1-410-614-4742 Lab: +1-410-614-4894 Fax: +1-410-955-2926 http://lupo.jhsph.edu
