Cara you have re-ignited the perennial Mac v PC debate!!! You'll be asking 
about depositing raw diffraction data next ;)

Cheers
Ashley

Sent from my iPhone

On 23/01/2013, at 10:29 PM, Anastassis Perrakis <[email protected]> wrote:

> I am of the opinion that the truth lies somewhere in between ...
> 
> Here are my two cents based on personal experience ...
> 
> For example, I am happy myself using a MacBook Pro, which is sufficient for 
> all my activities, and has all software and data that I need.
> Thus, I am myself on the 'new' paradigm side, having a machine with 
> "mainframe levels of storage and computing power" (I do not run git,
> but time machine in a mac has the bits I need from the git idea - as far as I 
> know git that is).
> 
> In the department, we have about 20-25 scientists. These people need to 
> ''maintain" and be proficient in many software suites, many more than
> a traditional crystallographer (like me in my PhD time for example) would 
> need:
> vector design software for cloning, databases for keeping track of clones, 
> sequencing viewing software for their clones, 
> interfaces for crystallisation and biophysical equipment, analysis suites 
> like Graphpad/Prism, Origin, Kintek (etc etc)  for biophysical experiments 
> ... 
> .... and lets not forget SAXS software ... Our experience, is that most of 
> these people like to use a Windows workstation for these (the choice is free),
> others prefer a Mac, thats not my point here. Many of that software also 
> needs to "maintained" by these people...
> Also, for a variety of reasons which have to do with IT "support" 
> restrictions, the Windows machines
> we have for them are miss-configured with ancient versions of the windows 
> "operating" system, but still Ok for many things, but not for really 
> straightforward use of CCP4/Phenix ...
> 
> My point here is, that these people are less likely to be keen of the idea to 
> also install and run ccp4/coot/phenix/buster in their machines 
> (they use pymol/yassara/chimera though locally since they can copy/paste to 
> their presentations and papers then). 
> So, we find it useful to keep an old fashioned setup running in parallel. 
> Linux boxes, hooked to Zalmans or really
> big or double LCDs, in a specific room ... People like these for data 
> processing, all data of many years back are online, incremental backup is 
> running etc.
> For historical reasons we even run NFS/NIS there (I agree its not a great 
> choice if one would start now).
> 
> My conclusion and advice for labs or departments that have more than 5-6 
> people, and are doing crystallography but not as their
> "full-time" business is that besides personal PC/Mac, a common room with a 
> few relatively powerful machines with nice, big, double,
> screens, likely also Stereo, is useful for a few reasons:
> 
> 1. Easier to make sure everybody is using the same software more or less
> 2. Same machine to everybody - not the situation that a new student gets a 
> new machine at year 0, which is redundant by graduation time at +3 years 
> (...or +5,6,7...)
> 3. Mixing of people in the room and ability for people to "look over the 
> shoulder" of others, the point that my colleague Titia Sixma always favours,
> which has indeed proved great for teaching others and learning from others.
> 4. Centralised "real" backup, availability of diffraction data on-line with 
> less "mounts"...
> 
> For these machines, centralised user account information and 'home' sharing 
> is in my view essential, as it allows to "blindly" choose any of the
> machines that is available at a time ... and, being a Mac fun, I think Linmux 
> is better suited for that purpose, financially and practically...
> 
> These said, it reminds me that we need to update the OS, buy a few new 
> machines, new LCDs ... argh.
> 
> Sorry of this lecture was outside the scope of the original thread.
> 
> Tassos
> 
> 
> 
> On 23 Jan 2013, at 9:54, James Stroud wrote:
> 
>> On Jan 22, 2013, at 11:20 PM, Nat Echols wrote:
>>> The real difficulty is integrating Macs into a
>>> Linux-centric environment, for example configuring NFS, NIS, etc.
>> 
>> That's because NFS and NIS are antiquities left over from the days of 
>> mainframes. Distributed file systems and user information databases are 
>> designed for an environment of many workers and few machines, when the 
>> typical graphics workstation cost $50,000. These days, we argue whether to 
>> spend an extra $200 on a $500 computer. We have moved to a new paradigm: 
>> many workers with many more machines, with each machine having 
>> essentiallymainframe levels of storage and computing power. In other words, 
>> instead of NFS, you should run git.
>> 
>> James

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