Why not? They can be mutually excluding! If one is in, the second can be. This 
phenomenon brakes a local symmetry.
FF

Dr Felix Frolow   
Professor of Structural Biology and Biotechnology, Department of Molecular 
Microbiology and Biotechnology
Tel Aviv University 69978, Israel

Acta Crystallographica F, co-editor

e-mail: mbfro...@post.tau.ac.il
Tel:  ++972-3640-8723
Fax: ++972-3640-9407
Cellular: 0547 459 608

On Jan 7, 2013, at 11:28 , Xiaopeng Hu <huxp...@mail.sysu.edu.cn> wrote:

> Dear All,
> 
> We recently resolved an enzyme/inhibitor complex structure. The enzyme 
> contains two NCS related active site and we did find extra density in both of 
> them.However we observed that the two inhbitor moleculors are not NCS 
> related, but partly overlaped if make a NCS moleculor. Has anyone else 
> observed this before? Thanks for any help and suggestion!
> 
> 
> Best,
> 
> Xiaopeng Hu
> 

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