1. SUBJECT: Postdoctoral Research Fellow in Structural Biology of Insulin Postdoctoral Research Fellow in Structural Biology of Insulin, Insulin - like Growth Factors. A postdoctoral position, funded by the Medical Research Council within an international Programme Grant: A molecular dissection of the interplay between diabetes and cancer: an integrated, multidisciplinary approach, is available to work with Programme co-ordinator Dr A. Marek Brzozowski in York Structural Biology Laboratory (YSBL), Department of Chemistry.
The project will involve functional and structural studies on novel insulin and Insulin-like Growth Factors and their complexes with the receptors, and the development of web-based Centre of Insulin Research in York. The project is closely linked with work of Institute of Organic Chemistry, Czech Academy of Sciences (Prague), University College Cork and Walter and Eliza Hall Institute of Medial Research (Melbourne). The Programme should lead to delineation of structural determinants of metabolic and growth properties of insulin and IGFs, and lead to development of their novel analogues for more efficient treatments of diabetes and cancer. Applicants should have a PhD in structural biology, biochemistry or related areas and some experience in X-ray crystallography and computational biology. Starting salary will be £30,122 per year. The post is available from November 2012 for a period of up to 5 years on a full time basis. To apply please go to: https://jobs.york.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=3885&p_web_page_id=156189 For informal enquiries please contact marek.brzozow...@york.ac.uk __________________________________________________________________________________ 2. SUBJECT: Postdoctoral Research Fellow in Insulin Receptor A postdoctoral position, funded by the Medical Research Council within an international Programme Grant: A molecular dissection of the interplay between diabetes and cancer: an integrated, multidisciplinary approach is available to work with Programme co-ordinator Dr A. Marek Brzozowski in York Structural Biology Laboratory (YSBL), Department of Chemistry. The aim of the project is to develop cloning, expression and production of new Insulin Receptor constructs for systematic structural studies of the hormone-receptor complexes. The project is closely linked with work of Institute of Organic Chemistry, Czech Academy of Sciences (Prague), University College Cork and Walter and Eliza Hall Institute of Medial Research (Melbourne). The Programme should lead to delineation of structural determinants of metabolic and growth properties of insulin and IGFs, and lead to development of their novel analogues for more efficient treatments of diabetes and cancer. Applicants are expected to have a PhD level qualification in human molecular biology, molecular endocrinology or biochemistry with experience in production of complex human proteins. Starting salary will be £32,901 per year. The post is available from November 2012 for a period of up to 5 years on a full time basis. To apply, please go to: https://jobs.york.ac.uk/wd/plsql/wd_portal.show_job?p_web_site_id=3885&p_web_page_id=156191 For informal enquiries please contact marek.brzozow...@york.ac.uk
