On Tue, Jun 12, 2012 at 8:53 PM, Frank von Delft <frank.vonde...@sgc.ox.ac.uk> wrote: > Finding 111 sites should be feasible without other tricks than very careful > data collection (see below); if you have two or more copies in the ASU, you > may find you need to do what the ribosome guys did, namely use other > derivatives (e.g TaBr clusters) to locate your seleniums, and then phase.
With 40% of the complex having homologues in the PDB, you may be able to place those subunits by MR, then use the phases from the incomplete model to locate the seleniums. -Nat
