*Postdoctoral Research Fellow – Macromolecular Crystallography* * Membrane Structural and Functional Biology – Caffrey Lab Trinity College Dublin, Ireland * Trinity College Dublin is inviting applications for the post of Postdoctoral Research Fellow in the Caffrey Membrane Structural and Functional Biology Research Group. The major theme within the Group is structure and function of membrane proteins by crystallographic means. Systems under investigation include human GPCRs, transducers, transporters, lipid metabolizing enzymes, respiratory complexes, and quorum sensing-related and biofilm forming membrane proteins of Pseudomonas aeruginosa. Purified protein and in meso-grown crystals of several targets are already in hand.
*Person Specification* - A Ph.D. in macromolecular X-ray crystallography - Experience and demonstrated success with macromolecular crystallization - Experience and demonstrated mastery of all of the computational aspects of crystal structure determination to include MR, MAD, SAD, MIR, and S/MIRAS - Experience with low-resolution structure determination - Experience and demonstrated mastery of the latest crystallographic software on UNIX-based operating systems to include the CCP4 suite, CNS, Phenix, Phaser, Sharp and other relevant packages - Recent experience and demonstrated mastery of on-site data collection at a synchrotron X-ray source - Availability and willingness to travel to synchrotrons and collaborators worldwide - A commitment to quality and innovative research The candidate should be a self-motivated individual who enjoys working as part of a collaborative, multidisciplinary team. Strong leadership, communication and teaching skills are decided assets. Salary: based on experience The closing date for receipt of applications is *Tuesday, 19th June 2012*. Further information for applicants and application material are available online from: www.tcd.ie/vacancies
