Hi Roger

CCP4 and Mosflm work fine in my testing - I do builds for Linux and Macs, both 32 and 64 bits. I wouldn't expect to see a difference in performance (and don't see anything significant in practice).

One thing - I think you will need to install 32-bit compatibility libraries for some of the code that is dynamically linked and has been built as 32-bit, e.g. I think ActiveTcl distros might need them (for iMosflm).

On 3 Apr 2012, at 20:57, Roger Rowlett wrote:

The time has come for me to upgrade my Linux OS to something more recent for me and my student workstations. A 32-bit distro is certainly conservative and compatible with CCP4 and Coot, but it seems like that solution hobbles my hardware and puts some limitations on available memory, even with PAE enabled. So who is using a 64-bit distro these days, and are there lingering issues of compatibility and dependency hell with commonly used XRD software, like CCP4, Coot, iMOSFLM etc.?

Ubuntu 12.04 LTS (beta) actually works OK with one simple workaround for the global menu for CCP4 and Coot, and wine compatibility is fine for running CrysalisPro in the same environment, so it's really comes down to whether or not the extra performance of a 64-bit OS is worth the pain of compatibility issues for XRD software. Any thoughts?

Cheers,

_______________________________________
Roger S. Rowlett
Gordon & Dorothy Kline Professor
Department of Chemistry
Colgate University
13 Oak Drive
Hamilton, NY 13346

tel: (315)-228-7245
ofc: (315)-228-7395
fax: (315)-228-7935
email: rrowl...@colgate.edu

Harry
--
Dr Harry Powell, MRC Laboratory of Molecular Biology, MRC Centre, Hills Road, Cambridge, CB2 0QH



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