Hello Deng, Process them as usual with e.g. Mosflm, then sort them together (you may need to rebatch one of the runs) and do one Scala run - this will put all of the measurement on a common scale and write out data suitable for refinement. For pointgroups with ambiguous origin choices (e.g. P4) you should also run the data through pointless to confirm you have made the same choice with both sweeps.
If you fancy, you can always run xia2 to do this, simply put all of the images into one directory and run xia2 -2d /here/are/the/images to use Mosflm and Scala or xia2 -3d /here/are/the/images to use XDS / XSCALE (provided you have those installed) Best wishes, Graeme On 13 March 2012 08:19, dengzq1987 <dengzq1...@gmail.com> wrote: > Hi CCP4bb, > > I have two dataset from one crystal with different distance.now i am > wondering how to merge the two dataset into one file,and use it to > refinement. > > > thanks a lot! > > > deng >