*Department: Biological Chemistry and Molecular Pharmacology Location: Longwood Ave., Boston, MA URL: http://hkl.hms.harvard.edu<http://www.cincinnatichildrens.org/research/div/dev-biology/fac-labs/hegde/default.htm> Start Date: immediate/negotiable Description: Our laboratory at Harvard Medical School has an immediate opening for an protein/RNA crystallographer. Our group recently determined high resolution X-ray structures of Lin28 with various members of let-7 microRNAs (Nam et al., Cell 2011), a system that has been implicated in control of cell differentiation, cancer, and cell stemness. Projects are available in our laboratory to build up on those recent results. As a member of our group you will utilize a variety of structural biology techniques, including X-ray Crystallography, SAXS, molecular dynamics and NMR (in collaboration with Prof. James Chou). You might also collaborate with members of Children’s Hospital Stem Cell Institute to perform complementary biological experiments.
Candidates must hold PhD in biochemistry or related fields. Strong background in molecular biology, biochemistry, large-scale protein expression and purification of proteins and nucleic acids is desired. Please submit: To apply, please send a single PDF file that incorporates CV including contact information of 3 references and list of your experimental expertise. Person to contact: Dr. Piotrek Sliz Surface mail address: Harvard Medical School. Department of Biological Chemistry and Molecular Pharmacology. Center for Molecular and Cellular Dynamics. 250 Longwood Ave., Rm SGM-130, Boston, MA, 02115. Email address: ap...@hkl.hms.harvard.edu* -- Piotrek Sliz Assistant Professor in Pediatrics Lecturer on BCMP Harvard Medical School Center for Molecular and Cellular Dynamics http://hkl.hms.harvard.edu Voice: (617) 299-1455
