Hello Rajintha,

> HKL-3000 version 701c3
> Checking program versions ...
> Error: could not read denzo_3d program version.
>
> Program output:
> dyld: unknown required load command 0x80000022
>
> In order to manually test the program run command:
> /usr/local/bin/denzo_3d

Apple introduced a compressed linkedit loader section in Mach-O binary
headers in 10.6; that error is the OS X 10.5 loader not understanding the
header fields. You can verify this is the case if you have the Xcode
development package installed.

On a 10.5.8 machine, you'll get output like this:

 $ otool -l denzo_3d | grep -A10 "Load command 4"
Load command 4
      cmd ?(0x00000022) Unknown load command
  cmdsize 48
00000000 00000000 00234000 00000088 00000000 00000000 00234088 000006f8
00234780 00004828
Load command 5
     cmd LC_SYMTAB
 cmdsize 24
  symoff 2330536
   nsyms 6088
  stroff 2429640

And on a 10.6 machine it will look like this:

 $ otool -l denzo_3d | grep -A10 "Load command 4"
Load command 4
            cmd LC_DYLD_INFO
        cmdsize 48
     rebase_off 0
    rebase_size 0
       bind_off 2310144
      bind_size 136
  weak_bind_off 0
 weak_bind_size 0
  lazy_bind_off 2310280
 lazy_bind_size 1784

I have filed this exact bug report with HKL Software in the past. If you
wait long enough, they will usually compile a version that runs on 10.5
machines. The support email for HKL Software is supp...@hkl-xray.com. No
one here can help you.

Have you tried iMosflm?

-ben

--
| Ben Eisenbraun
| SBGrid Consortium                          | http://sbgrid.org       |
| Harvard Medical School                     | http://hms.harvard.edu  |

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