Dear Chris A whole series of studies from the early to late 90's did his for the growth hormone-GHR interaction. Papers by Pearce, Cunningham, Clackson and Wells come to mind. Also a recent study on the IL13-IL13R interaction by Lupardus et al has covered most of the interaction epitope.
Best regards Savvas On 07 Feb 2012, at 10:16, Chris Ulens <chris.ul...@med.kuleuven.be> wrote: > Dear colleagues, > I am looking for a few example studies in which a complete mutagenesis of all > residue-ligand interactions has been conducted to evaluate the energetic > contributions of each individual interaction. > Thank you. > Best regards. > -Chris > > --------------------------------------------------- > Chris Ulens, Ph.D. > Lab of Structural Neurobiology > Department of Cellular and Molecular Medicine > Campus Gasthuisberg, ON1 > Herestraat 49, PB 601 > B-3000 Leuven > Belgium > e chris.ul...@med.kuleuven.be > t +32 16 330689 > f +32 16 345699 > w http://www.xtal.be
