Dear Crystallographers,

I cannot think why any of the various flavors of Rmerge/meas/pim
should be used as a data cutoff and not simply I/sigma--can somebody
make a good argument or point me to a good reference? My thinking is
that signal:noise of >2 is definitely still signal, no matter what the
R values are. Am I wrong? I was thinking also possibly the R value
cutoff was a historical accident/expedient from when one tried to
limit the amount of data in the face of limited computational
power--true? So perhaps now, when the computers are so much more
powerful, we have the luxury of including more weak data?

JPK


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Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
email: j-kell...@northwestern.edu
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