Hey Narayanan Not sure about about your spelling or capitalization but I am assuming the O is a mistake. The, MiU is mega international units. mcg is microgram ( when Greek symbol can't be typed).
You will need to know the assay that measures activity for G-CSF (filgrastrim). Then the standard reference for specific activity in units per mg or mcg of filgrastrim. Conversion should follow. So for Neuprogen, Filgrastim has a specific activity of 1.0 ± 0.6 x E08 U/mg (as measured by a cell mitogenesis assay), or 100 MU/mg, or 0.1 MU/mcg. (NB R&D is Research and Development in Pharmaceutical acronym.) Dexter Kennedy Genentech, Inc. iPawed from my iPad On Jan 19, 2012, at 8:33 AM, Narayanan Ramasubbu <ramas...@umdnj.edu> wrote: > On 1/19/12 5:32 AM, Tim Gruene wrote: >> -----BEGIN PGP SIGNED MESSAGE----- >> Hash: SHA1 >> >> Hi Megha, >> >> your email could hardly be more cryptic to me, and maybe you increase >> the chance of getting help by explaining >> - - what is R& D >> - - what is MiOU? >> - - what is mcg? (milli-centi-gram?) >> (I understand ml, but I do not remember having met any of those other >> units). >> >> Cheers, >> Tim >> >> On 01/19/2012 03:58 AM, megha goyal wrote: >>> We are involved in R& D of recombinant filgrastim and the standard sample >>> label mentions it as 30MiOU/ml i.e 300 mcg/ml. How can we determine the >>> IU/ml as we know our protein is 300 mcg/ml. can anyone please guide me on >>> the corelation. >>> >>> regards, >>> >>> megha >>> >> - -- - -- >> Dr Tim Gruene >> Institut fuer anorganische Chemie >> Tammannstr. 4 >> D-37077 Goettingen >> >> GPG Key ID = A46BEE1A >> >> -----BEGIN PGP SIGNATURE----- >> Version: GnuPG v1.4.10 (GNU/Linux) >> Comment: Using GnuPG with Mozilla - http://enigmail.mozdev.org/ >> >> iD8DBQFPF/EtUxlJ7aRr7hoRAk6VAKDL7l0sN0R5PigjSd8cfA3bKB94lwCfSM8i >> zfVXB/IzdZnHJrI/0xj4aUY= >> =X/M9 >> -----END PGP SIGNATURE----- >> > Would these be > R&D - Research and Development? > mcg = microgram > IU/ml = International Units?/ml > > I have no idea about MiOU? Probably some optical unit? > > Subbu
