Hi,

Regardless of what the consensus on naming for the technique, I'd suggest you combine these datasets during phasing (I'm aware of MLPHARE, SHARP, PHASIT supporting multiple anomalous datasets during phasing; others probably do as well). Combining at the merging step (pointless/scalepack/etc) might result in averaging amplitudes collected at different wavelengths (and therefore with different anomalous signal): and since your phases will come from amplitude differences this may result in less reliable phases.

Pete

arka chakraborty wrote:
Hi all,

I have two datasets, both CO SAD data, one collected at  CO anomalous 
wavelength at synchroton and the other at home source. I wish to combine these 
two data-sets and use for SAD phasing. Can anyone suggest how this can be done?

Regards,

ARKO

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ARKA CHAKRABORTY
CAS in Crystallography and Biophysics
University of Madras
Chennai,India


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