On Thu, 2011-12-08 at 12:17 +0530, atul kumar wrote:
> I can't build anything in this region,this could be because of
> disordered structure or because of low resolution.
Both, and also the presence of disordered fragment may be the reason the
resolution is low, thus the already mentioned suggestion to remove it
(unless, of course, that renders your protein inactive and thus
compromises your structure-based conclusions).
> what are the things which I can try to improve this?
If the region in question is disordered in solution, pretty much
nothing. Look for a different crystal form.
Having a disordered region does not make your structure invalid. In
fact, it may be important for understanding the biological role of the
protein.
--
"I'd jump in myself, if I weren't so good at whistling."
Julian, King of Lemurs
